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Eric Szelenyi redonda
Eric Szelenyi, PhD.

contacto 02 ericszelenyi@gmail.com

Research group: NeuroPuentes: Neuroevolutionary Systems Biology Group

 

 

 

Research Areas: Deconstruction of distributed neural circuits and their function in health and disease / Discovery and characterization of biodiversity-derived neurochemical systems from plants and animals / Neuroimmune mechanisms underlying anxiety, depression, and neurodegenerative disorders / Computational approaches to behavioral and neural circuit phenotyping, and molecular modeling / Molecular genetic tool development for high-throughput neural circuit discovery and brain receptor target engagement

 

Investigacin actual   Current research:

NeuroPuentes investigates biodiversity-derived neurochemical systems and their capacity to influence neural circuits and neuroimmune function in the mammalian brain. The program integrates molecular discovery from plant and animal sources with quantitative circuit analysis and computational modeling to connect molecular interactions to large-scale brain dynamics.

By treating naturally occurring neuroactive repertoires as structured biological probes, the group seeks to understand how coordinated molecular perturbations reshape neural and neuroimmune states, revealing fundamental principles of brain regulation and dysfunction.

Estudios  Education and Academic Positions:

  • 2026–Present. Visiting Professor/Researcher, NeuroPuentes: Neuroevolutionary Systems Biology Group, CISeAL, Pontificia Universidad Católica del Ecuador.
  • 2024–2026. Acting Assistant Professor, Neurobiology and Biophysics, University of Washington, USA.
  • 2019–2024. Postdoctoral Fellow, Department of Biological Structure, University of Washington, USA.
  • 2017–2019. Scientist I, Allen Institute for Brain Science, Seattle, USA.
  • 2010–2017. PhD in Neuroscience, Stony Brook University (Cold Spring Harbor Laboratory), NY, USA.
  • 2006–2010. Biological Research Assistant, U.S. Army Research Institute of Environmental Medicine (USARIEM), USA.
  • 2006. BA in Psychology (Biochemistry concentration), Shippensburg University of Pennsylvania, USA.

 

Publicaciones recientes Recent Publications 

  • Szelenyi ER and Urso ML (2012). Time-course analysis of injured skeletal muscle suggests a critical involvement of ERK1/2 signaling in the acute inflammatory response. Muscle & Nerve 45(4):552-61. DOI: https://doi.org/10.1002/mus.22323
  • Graybuck LT, Daigle TL, et al., Szelenyi ER (2021). Enhancer viruses for combinatorial cell-subclass-specific labeling. Neuron 109(9):1449-1464. DOI: https://doi.org/10.1016/j.neuron.2021.03.011
  • Matho KS, Huilgol D, et al., Szelenyi ER (2021). Genetic dissection of the glutamatergic neuron system in cerebral cortex. Nature 598(7879):182-187. DOI: https://doi.org/10.1038/s41586-021-03955-9
  • Szelenyi ER, Goodwin NL, Golden SA (2021). Social mice seeking circuits. Nature Neuroscience 24(6):761-762. DOI: https://doi.org/10.1038/s41593-021-00861-1
  • Madangopal R*, Szelenyi ER*, et al. (2022). Incubation of palatable food craving is associated with brain-wide neuronal activation in mice. PNAS 119(45). (Author contribution) DOI: https://doi.org/10.1073/pnas.2209382119
  • Ishii KK, Hashikawa K, et al., Szelenyi ER (2025). Post-ejaculatory inhibition of female sexual drive via heterogeneous neuronal ensembles in the medial preoptic area. eLife. DOI: https://doi.org/10.7554/elife.91765
  • Szelenyi ER#, et al. (2024). Distributed X chromosome inactivation in brain circuitry is associated with X-linked disease penetrance of behavior. Cell Reports. (Corresponding author) DOI: https://doi.org/10.1016/j.celrep.2024.114068
  • Goodwin NL et al., Szelenyi ER (2024). Simple Behavioral Analysis (SimBA) as a platform for explainable machine learning in behavioral neuroscience. Nature Neuroscience. DOI: https://doi.org/10.1038/s41593-024-01649-9
  • Szelenyi ER#, et al. (2024). An arginine-rich nuclear localization signal (ArgiNLS) strategy for streamlined image segmentation of single cells. PNAS. (Co-corresponding author) DOI: https://doi.org/10.1073/pnas.2320250121
  • Ben-Simon Y et al., Szelenyi ER (2025). A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types. Cell. DOI: https://doi.org/10.1016/j.cell.2025.05.002

 

Redes  ResearchGate: https://www.researchgate.net/profile/Eric-Szelenyi