CISeAL researchers Dr. Xavier Sánchez, Dr. Ruth Jimbo-Sotomayor, and Dr. Andrés Moreno participated in the publication of a clinical case describing the atypical presentation of a Frantz-Gruber tumor or solid pseudopapillary neoplasm of the pancreas, a rare neoplasm with low malignant potential that can be mistaken for other cystic pancreatic lesions. The study presents the case of a 15-year-old female patient who, after suffering abdominal trauma with a pancreatic injury, developed recurrent epigastric pain, nausea, and vomiting. Imaging studies showed a lesion in the head of the pancreas with a cystic component and central calcifications, leading it to be initially interpreted as a post-traumatic pancreatic pseudocyst. However, during the surgical intervention, a pancreatic mass was identified that prompted a Whipple procedure. Although the intraoperative study initially suggested a mucinous neoplasm, definitive histopathological analysis and immunohistochemistry confirmed the diagnosis of solid pseudopapillary neoplasm, with positivity for β-catenin, vimentin, and progesterone receptor, alongside a Ki-67 proliferation index of less than 1%, which are characteristic findings of this type of tumor.
This study, in which our researcher Dr. Ana Lucía Moncayo participated, presents the protocol for an impact evaluation of Brazil's Continuous Cash Benefit (BPC), a non-contributory pension program aimed at adults aged 65 and older and people with disabilities living in poverty. The objective is to determine whether this financial support reduces hospitalizations and mortality by improving living conditions, access to food, medical care, and other social determinants of health. To achieve this, a natural experiment design with quasi-experimental methodologies will be used, allowing for more robust estimation of causal relationships than traditional observational studies.
The mental health of medical students represents a growing challenge for higher education institutions due to high academic demands, long hours of study and clinical practice, and the frequent adoption of unhealthy habits during their training. In Ecuador, where Medicine is one of the most in-demand majors, there is little evidence regarding the magnitude of this problem. To help fill this gap, CISeAL researchers Xavier Sánchez and Ruth Jimbo-Sotomayor, along with faculty members from the School of Medicine and the Family Medicine Postgraduate Program at PUCE, conducted a study on 393 medical students at the Pontifical Catholic University of Ecuador to assess the presence of symptoms of depression, anxiety, risky alcohol consumption, and their relationship with various health behaviors and sociodemographic factors.
Why, despite economic growth and advances in education and health, does early motherhood continue to disproportionately affect young women in situations of greatest vulnerability? Dr. Ana Lucía Moncayo participated in a study that analyzed the relationship between household income and early motherhood in Mexico based on data from the 2000, 2010, and 2020 national censuses, which included information from more than 30 million women aged 12 to 24. To understand this phenomenon from different perspectives, the researchers combined machine learning tools, Bayesian spatial models, and dynamic structural equation models, which made it possible to evaluate both individual factors and territorial differences associated with early motherhood.
Dr. Venus Medina Maldonado participated in a study that evaluated the psychometric properties and relational structure of the Brief Adverse Childhood Experiences Abuse Short Form (ACE-ASF) among homosexual and heterosexual individuals in Ecuador. The study included 520 participants and aimed to determine whether this instrument reliably and validly measures experiences of physical, emotional, and sexual abuse during childhood, as well as to explore how these experiences are associated with the perception of abuse in intimate relationships during adulthood.
The results demonstrated that the ACE-ASF has high internal consistency and a structure composed of two clearly defined dimensions: physical-emotional abuse and sexual abuse. Furthermore, the instrument was found to maintain its validity and stability regardless of sexual orientation and variables related to the perception of abuse, such as feeling afraid, feeling trapped, or perceiving oneself as being abused in a relationship. These findings support the use of the scale as a robust tool for assessing traumatic experiences across different contexts and populations.
The following study, which involved our CISeAL researcher Venus Medina, analyzes how Ecuadorian women perceive nursing support and the use of non-pharmacological strategies to relieve pain during labor. Through a qualitative approach carried out at the Nueva Aurora Gyneco-Obstetric Pediatric Hospital in Quito, the experiences of 21 women in the immediate postpartum period were collected, revealing that interventions such as guided breathing, walking, sphere therapy, music therapy, and emotional support significantly contributed to transforming childbirth into a more tolerable, safe, and humanized experience. The findings show that participants not only perceived a reduction in pain and anxiety, but also experienced a greater sense of autonomy, calmness, and connection with their newborns.